2-((2-(2,6-DIOXOPIPERIDIN-3-YL)-1,3-DIOXOISOINDOLIN-4-YL]OXY]ACETIC ACID
2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetic acid
CAS: 1061605-21-7
Molecular Formula: C15H12N2O7
2-((2-(2,6-DIOXOPIPERIDIN-3-YL)-1,3-DIOXOISOINDOLIN-4-YL]OXY]ACETIC ACID - Names and Identifiers
2-((2-(2,6-DIOXOPIPERIDIN-3-YL)-1,3-DIOXOISOINDOLIN-4-YL]OXY]ACETIC ACID - Physico-chemical Properties
| Molecular Formula | C15H12N2O7 |
| Molar Mass | 332.27 |
| Density | 1.606±0.06 g/cm3(Predicted) |
| Boling Point | 660.5±55.0 °C(Predicted) |
| Solubility | DMSO : 42 mg/mL |
| pKa | 2.95±0.10(Predicted) |
| Storage Condition | 2-8℃ |
2-((2-(2,6-DIOXOPIPERIDIN-3-YL)-1,3-DIOXOISOINDOLIN-4-YL]OXY]ACETIC ACID - Preparation solution concentration reference
| 1mg | 5mg | 10mg | |
|---|---|---|---|
| 1 mM | 3.01 ml | 15.048 ml | 30.097 ml |
| 5 mM | 0.602 ml | 3.01 ml | 6.019 ml |
| 10 mM | 0.301 ml | 1.505 ml | 3.01 ml |
| 5 mM | 0.06 ml | 0.301 ml | 0.602 ml |
Last Update：2024-01-02 23:10:35
2-((2-(2,6-DIOXOPIPERIDIN-3-YL)-1,3-DIOXOISOINDOLIN-4-YL]OXY]ACETIC ACID - Reference Information
| biological activity | Thalidomide-O-COOH (Cereblon ligand 3, E3 ligase Ligand 3) is a Thalidomide-based Cereblon (CRBN) ligand that can be used to recruit CRBN proteins. Thalidomide-O-COOH (Cereblon ligand 3) can be connected to the ligand of the protein through a connector to form a PROTACs (Proteolysis Targeting Chimera). |
| target | TargetValue CRBN () |
| Target | Value |
| Use | A ligand for E3 ubiquitin ligase in PROTAC technology. |
Last Update：2024-04-09 21:11:58
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Product Name: 2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetic acid Request for quotation
CAS: 1061605-21-7
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CAS: 1061605-21-7
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Email: chenmengqi@highfine.com
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merry@highfine.com
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View History
2-((2-(2,6-DIOXOPIPERIDIN-3-YL)-1,3-DIOXOISOINDOLIN-4-YL]OXY]ACETIC ACID
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8-氟2-三氟甲基-4-羟基喹啉
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C.I.15825
METHYL (5-CHLOROMETHYL-DIHYDROFURAN-2-YLIDENE)ACETATE
ethyl 2-cyanobenzoate
2-羟基-5-甲基苯甲酸甲酯
2-Methoxy-4-nitrophenol
2-Propenoic acid, 2-methyl-, polymer with butyl 2-methyl-2-propenoate, 2-hydroxyethyl 2-methyl-2-propenoate and methyl 2-methyl-2-propenoate
8-氟2-三氟甲基-4-羟基喹啉
双(2,4,6-三甲基吡啶)碘六氟磷酸盐
2-Methoxy-5-(Trifluoromethoxy)Acetophenone
C.I.15825
METHYL (5-CHLOROMETHYL-DIHYDROFURAN-2-YLIDENE)ACETATE
ethyl 2-cyanobenzoate